23. Holland Taylor as Evelyn Harper on Two And A Half Men

Evelyn walks around with the air of a woman who has genuine affection for her two sons, Alan and Charlie (Jon Cryer and Charlie Sheen), and grandson, Jake (Angus T. Jones), but really she's one of the most superficial people alive, way more concerned with her wealth and lifestyle. Prime example: In between dramatic sobs during Charlie's funeral, she drops hints about selling his house (she's a realtor) with zero subtlety. She also keeps quite, um, busy in the bedroom, even giving Ashton Kutcher's Walden Schmidt an official "welcome" to town this season.