14. Space Ghost Coast To Coast (1994-2001, Cartoon Network; 2001-2004, Adult Swim)
Space Ghost basically gave birth to the Adult Swim style of animated humor; sadly, though, it never quite garnered the respect that inferior Aqua Teen Hunger Force and The Venture Brothers have enjoyed. And aside from the copious amount of laughs that each episode provided, what's most memorable about the show was its completely original concept. Coast To Coast was, essentially, a talk-show starring the classic ‘toon character Space Ghost as the host.
The humor was very dry, and often mundane, but it was also extremely well done, and the celebrity interviews were almost always classic. For years, it was the glue that held Adult Swim together, even as other shows went on to gain more popularity in the realm of video games and movies.