2. Seth

GAME: Street Fighter IV (PS3/360, 2009)
Back in the day, M. Bison drove us nuts, but Seth took that "impossible to beat boss" thing waaaay too far. Street Fighter IV was actually a good game—a damn good one—until we got to Seth and pretty much had to put the game on easy just to get all the endings. And we still haven't seen Zangeif's conclusion. That move where he sucks you in gets us every time. Every time. You cheap piece of shit, just die already. Please?