10. THE STUFF IN THE STUFF (1985)More of a comedy than a horror film, The Stuff tells the story of an addictive goo that turns people into mindless zombies after eating it.
So that means the main villain of the film is just this strange liquid. No axe murderer, no demons, no zombies. Just a sloppy liquid similar to the kind you'd find in any unkempt college dorm. Lame.
The Stuff comes pretty close to having the worst villain in cinematic history, but M. Night Syamalan's inclusion of killer trees in The Happening just edges it out.