The iHeart Radio Music Festival is set to invade Las Vegas once again in September, and this year, they're going all out with a headlining cast of Kanye WestJanet JacksonSam Smith, and The Who. This will be Kanye's first ever performance at the festival, which is set to take place at the MGM Grand Arena on September 18 and 19. Along with the headliners, performers during the event will also include The WeekndLil WayneDisclosureDiploTrey Songz, and many more. The full list of acts for the event can be seen below. 

Kanye West
Sam Smith
The Who
Demi Lovato
David Guetta
Kenny Chesney
The Weeknd
Tove Lo
Lil Wayne
Fall Out Boy
Disclosure
Hozier
Jason Derulo
Duran Duran
Prince Royce
Diplo
Trey Songz
The Killers
Blake Shelton
Nick Jonas
Janet Jackson