The Predator 2 for PC.
Year of release: 1990
A title that leaped over an NES release, but made an appearance on the Sega Genesis and PC. The game was set in L.A. and was based on the 1990 Danny Glover-centric Predator 2. The film is remembered most fondly for attempting to pass off Gary Busey as a scientist and having Danny Glover defeat the Predator in a fist-fight.
Yeah, suspension of disbelief is completley mandatory. Predator 2 the game, on the other hand, was an on-rails shooter that is hilariously forgettable. Rescuing hostages and avoiding attacks from the Predator made this isometric shooter an uninspired affair, but reinforced the Predator's staying power as a pop-culture action mainstay.