NCAA Player Likeness Lawsuit
Unlike a similar lawsuit for Madden, the NCAA litigation is still occupying the courts. If you want to know how severe it could be, some have speculated it would be the end of the NCAA Football franchise (and thanks to their own exclusivity deal that would be the end of video game college football).
In 2009, former Arizona State and Nebraska quarterback Sam Keller sued EA for the use of amateur athlete's likeness' (probably had something to do with being waived by the Raiders in 2008). Over the course of the next couple years several other athletes (including Bill Russell) added their name to a class action suit. It hasn't officially rocked the sports gaming world yet, but it is an issue that isn't going away. It also could help explain your confusion in the future when Johnny Heisman is black and Kain Colter is white.