50. Ico (2001)
Ico's opening is as much a mood-setter as it is expository. It starts off almost peacefully and serene and ends ominously in ways only captivity and solitude can evoke. Back when this game came out a decade ago, its visual design, particularly its naturalistic color palette stood out from the pack of PlayStation 2 games. Now it has influenced everyone from Hideo Kojima to thatgamecompany.