50. Issey Miyake
Highly influential designer Issey Miyake revolutionized pleats forever. By finding a way to make pleats that help movement and are easier to produce, he made a logistical innovation in the fashion industry. Miyake's concepts and visions have a lot to do with innovation, like his A-POC collection, which consists of garments simply made out of one piece of cloth. Miyake is also the designer that defined Steve Jobs' uniform—he's the man behind Jobs' trademark black mock turtlenecks.