Doctor Octopus (circa Ultimates)
Artist: Mark Bagley
No longer a flabby old nerd with bad eyesight, the brolic, badass Doc introduced in Ultimate Spider-Man is definitely getting that octopussy (heh). Black shades hide grisly scars where his eyes used to be, and psychically-controlled metal arms are fused into his green and blue suit. Best of all, Ock's accessory game is unparalleled—the "nanobots" at the end of each arm can morph into anything he wants, from flamethrowers to machine guns.