Team: New England Patriots
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After a promising collegiate career in which he battled multiple injuries, Edwards looked like a future star after rushing for 1,115 yards and nine touchdowns in his first season with the New England Patriots. Unfortunately, he chose to participate in the NFL Rookie Beach Bowl at the Pro Bowl, one of the most ill-conceived ideas in league history. While playing, Edwards managed to partially or completely tear all four major knee ligaments (ACL, MCL, PCL, and LCL) as well as cause significant damage to the surrounding nerves. He nearly lost his leg in the surgery, but battled through an arduous three years of rehab to return in 2002 for the Dolphins as a third down back before ultimately concluding his career in the CFL.