Round: Sweet 16
Game: Mississippi St. vs. Loyola (Ill.)
Year: 1963
Watch It Here

It seems like it's lending false gravity to a sporting event when you call it "important," but this 1963 matchup of Mississippi St. and Loyola (Ill.) was just that. The Mississippi St. squad defied an order of the Mississippi governor, leaving the state to play against a team made up primarily of African-American players. This show of unity and togetherness through sports was an important lesson for a nation still battling against segregation, and served as a touchstone moment for college basketball as more programs began to embrace racial integration.