A.K.A.: Santa Monica Freeway
Route: Santa Monica to the East L.A. Interchange
Constant traffic that's thicker than Beyoncé's booty and new construction-related detours springing up every week make the 10 Freeway a permanent headache. Unlike the others on the list, the 10 doesn't get any better on the weekends. The sections to watch out for that get hit the hardest are near the 405 and 110 intersections. If you're coming from the South Bay, make sure to leave an hour and a half early to make it to that evening Laker game at Staples.