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49. Peyton Manning's Career Is Threatened

Date: 10/22/2006
Victim: Peyton Manning, Indianapolis Colts
Hit By: Andre Carter, Phillip Daniels, Washington Redskins

You know that neck surgery that Peyton had that caused him to miss the entire 2011 season and was subsequently the reason why the Colts opted to let him go? Well, this is the hit that caused all of that.

Tags: most-brutal-nfl-hits, ray-lewis, james-harrison, nfl, 2012-nfl-season
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