AGE: 37 (June 19, 1903 â€“ June 2, 1941)
CAUSE OF DEATH: Amyotrophic lateral sclerosis (ALS) a.k.a. Lou Gehrig's disease
COMPLEX SAYS: Considered by many to be the greatest first baseman of all-time, Gehrig racked up six World Series rings, two AL MVP titles, and a Triple Crown award during his 15-season career. The Iron Horse will forever be remembered for his durability which carried him through 2,130 consecutive games from 1925 to 1939 despite several injuries. Gehrig's streak and career came to a halt as the effects of a motor neuron disease known as ALS became overwhelming for the slugger. Less than two years after his "Luckiest Man on the Face of the Earth" speech at Yankee Stadium, Gehrig succumbed to the disease that would later be named after him.