Year: 2007
How Much Money He's Making: $25 million
What Will's Doing: Holding down Manhattan by himself with his dog. When a cure to cancer accidentally turns most people into pale nocturnal zombies (whoops!), Will shacks up in a fortified brownstone, hunts for deer in Times Square and runs relentless experiments for a cure. He delivers this generation’s Old Yeller moment when he chokes out his soon-to-be-zombified pooch while whispering the lyrics to "Three Little Birds." The mutants compromise his pad just as he discovers the vaccine. And so, to save the planet for the fifth time, Will sacrifices himself so the mother and son he met can take the vial of salvation for wide distribution. The blockbuster proved Will doesn’t need supporting actors to gross a quarter billi.