So it's not really surprising when he kidnaps Walter and Jesse and holds them hostage in the desert, where he takes care of his ailing uncle, Hector "Tio" Salamanca.
Knowing that Tuco has no plans of letting them out of here alive, Walt and Jesse concoct a plan to poison Tuco. And while Tio cannot speak, he can ring a bell to communicate to his nephew that his life is in danger. Unfortunately for Tuco, Walter's got family, too. Including Hank, who has taken time off from the DEA to look for his missing brother-in-law.
His investigation takes a bit of a detour and just so happens to bring Hank to Tuco—and just in time, too. Hank kills Tuco before Walt has to do it (though no one ever even knows that Walt was there).