Played by: Winona Ryder and Christian Slater

Growing up, if you couldn't stand the people around you, J.D. and Veronica's lethal union was the ultimate beacon of hope that yes, there was a ride-or-die girl out there who felt the same way. Although their dates consisted of killing off the obnoxious people who made high school hell (over the usual dinner-and-a-movie), the way they had each other's backs was totally admirable.

[GIF via]