68. Rose Byrne
Biggest accomplishment this year: Co-starring in next month's The Internship, alongside Vince Vaughn and Owen Wilson
Ever since her fantastic performance in Bridesmaids, Byrne has seen her popularity take off and her volume of film roles rapidly expand. She recently appeared with Ryan Gosling and Bradley Cooper in The Place Beyond the Pines, and will also appear in the upcoming comedy The Internship with Owen Wilson and Vince Vaughn. She also locked down a leading role in I Give It a Year, a British marriage comedy destined to be quirky, awkward, and probably a box office dud when it's released in August no matter how good it is.