39. Angelina Jolie
Biggest accomplishment this year: Bringing attention to genetic testing by announcing that she had a double mastectomy in February
Perhaps the most famous woman in the world, Jolie made headlines recently for her decision to undergo a preventative double mastectomy to protect against breast cancer. While she hasn't done much acting in recent years, she is scheduled to star in 2014's Maleficent alongside Elle Fanning and Sharlto Copley. It was also announced earlier this year that she will be working with the Coen brothers to make Unbroken, an adaptation of a popular biography about a World War II POW.