Played By: Wayne Knight

Villainy doesn't always show itself in grand gestures. Wayne Knight's portrayal of Newman on Seinfeld showed the world that repeated, tiny nuisances can be just as villainous as plots of world domination.

We all have that person in our life that we're convinced was put on Earth to irk us, whose every action irritates us. When you look back on your longstanding animosity with that person, you realize, as do Jerry and Newman, that after years of back-and-forth needling at each other, you don't even remember how you came to be enemies in the first place.