Oscar-worthy Movie: The Fighter (2010)

Adams has come a long way from playing the maniacal socialite that makes a girl climax on a horse in Cruel Intentions 2. (Yes, you can watch this on YouTube.) For six long years, she took the roles no one else wanted before getting the opportunity to demonstrate her gifts in Junebug, the role that earned her her first Academy Award nod. Since then, she's been the subject of major casting news and Oscar-buzz updates. 

Although the four-time nominee could break her losing streak if she upsets Anne Hathaway for this year's Best Supporting Actress award, it's hard not to dwell on the fact that she lost to her castmate Melissa Leo for her amusing turn as the sultry no-non-sense bartender, Charlyne, in The Fighter.