Played by: Karl Urban
In a franchise filled with hired guns, it’s hard to choose just one. Still, we're going with Karl Urban’s performance as the ruthless Kirill. He makes an impact at the beginning of The Bourne Supremacy by shooting Jason Bourne’s girlfriend, Marie (Franka Potente), through the head while the two of them are driving over a bridge. This sends Bourne into a suspected watery grave, while his lady is stone cold dead.
From there, Bourne goes after Kirill in what's one of the cinema's best high-speed car chases during Supremacy's final moments. Kirill in one of the only genuinely evil hitmen included in this list, and with good reason.