Why pair a flying rodent with a couple of wisecracking magpies? Why the fuck not? Mighty Mouse was the flying mouse (no shit you say, but here's something you didn't know: MM creator Izzy Klein's original super-powered vermin was a housefly named "Superfly"), and Heckle and Jeckle were the magpies, and along with new characters Quacula (a vampire duck) and Swifty (the sidekick to longtime Mighty Mouse adversary Oil Can Harry) they formed one of the most bizarre anthropomorphic menageries in animated history. Which is saying something.
44. The New Adventures of Mighty Mouse and Heckle & Jeckle (CBS, 1979-1982)