42. The Littles (ABC, 1983-1985)
Talk about international. Based on characters by an American author, produced by a French/Canadian studio, and animated by a Japanese studio, The Littles took the original story of a miniature, meddlesome family of mouse-humans a bit further. It being the '80s, the show touched on the perils of drug abuse (crack), abandonment, and the dangers of trusting really tall white guys (Ronald Reagan). Lessons learned, thankfully.