1. A man, a horse, and a perforated colon in Zoo (2007)
Out of respect for the dead, talking about the bizarre 2007 documentary Zoo requires a certain amount of tact. True, it'd be easy to crack wise about a guy who died due to complications from having sex with a horse; to be specific, he acquired peritonitis after letting the Seabiscuit lookalike be the giver during anal intercourse. But zoophiles are really out there, and, as heinous as their preferences may be, they are people, and knowing that Kenneth Pinyan lost his life as a result of his horse attraction is sad, not funny.
Granted, it's also cause for men to clench their derrieres in secondhand agony, but that's neither here nor there.