Funniest Role: Fran Fine on The Nanny
Memorable Quote: "Who would make this [voice] up?"

The first thing that comes to mind when you think of Fran Drescher is her insufferable voice. Yes, it's very annoying, but that's her thing. It's what makes her stand out from the other actresses who have come and gone during her career, which now spans over 35 years. Her 145-episode run as Fran Fine on The Nanny earned her Golden Globe and Emmy nods, and although she never came away with any hardware, it doesn't take away from the fact that for a solid period of six she was one of only a handful of famous funny girls on TV.