Greg the Bunny (Season 1)
Stars: Seth Green, Eugene Levy, Sarah Silverman, Bob Gunton
Before there was Seth MacFarlane's Ted, about a crude talking teddy bear and its human best friend (Mark Wahlberg), there was Greg the Bunny, about a crude talking puppet and his human BFF (Seth Green). So, yes, the similarities are a bit uncanny, but that's beside the point here.
Over the course of its three eccentric, consistently humorous, and sadly forgotten seasons (one on Fox and two on IFC), Greg the Bunny used its sharp writing, absurdly magic-realist concept, and impressive cast (Green, Eugene Levy, and Sarah Silverman) to its advantage; it's easy to accept a world in which a hand puppet sleeps with women when you're laughing so damn much.