Air Dates: September 13, 2005 - Present
Network: The WB/ The CW
Best Episode: "All Hell Breaks Loose" (May 10, 2007)

On paper, Supernatural seems like a show a dude's little sister should love, not her older brother. For one, it's on The CW, a.k.a. the land of teenybopper soaps and Seventeen magazine pin-ups. And that's exactly what Supernatural stars Jensen Ackles and Jared Padalecki are, two hunky actors who'd be treated as gods if they walked through an all-girl high school's cafeteria. What makes the show work so well, however, is that Ackles and Padalecki are actually anything but lame pretty-boys; having formed a seamless chemistry together, they're the perfect leads for a genuinely disturbing yet still accessible monster show.

The duo plays brothers Dean and Sam Winchester, respectively, siblings tasked with hunting down creatures, demons, and other abnormal baddies across the country. Now on its seventh season, Supernatural has sustained its intriguing narrative through rich mythology; portals into other dimensions have been opened, main characters have died and eventually resurrected, and Lucifer himself has become a major character. Not bad for a show that could've been The Hardy Boys by way of Twilight.