The scenes from last year's Deadly Premonition could have taken up half of this Top 50 list but instead we'll award it the #2 spot, exemplified with this classic discussion over “the sinner's sandwich”. Has David Lynch seen this game? Because it's the closest thing we've ever had to a Twin Peaks game, in the most twisted way imaginable (that's the point, right?).
4. Deadly Premonition (2010)