We’ll try not to spoil too much on this one, because her story deserves to be experienced first hand.  The final curtain for The Boss’ arc is heart-crushing, and no other villainess in gaming history has been given such full-blooded treatment by either protagonist (Snake) or creator (Hideo Kojima).

If you haven’t already played MGS3, do it now.  You’ll see why #1 was a no-brainer for us.  And you’ll see why she was truly the origin of Metal Gear lore.