10. MR. TINKLES IN CATS AND DOGS (2001)
Of all the mad villains’ plots in pop culture, Mr. Tinkles’ is one of the most infuriating. A white Persian kitty with Stewie Griffin-like delusions of world supremacy, Tinkles (voiced by Sean Hayes), the main antagonist in the highly unwatchable Cats & Dogs, is devoted to finding a way to make all humans allergic to dogs.
So, yeah, the little pussy bastard wants you to get rid of your best friend, the canine pal who’s always there when your days are lousy or your girlfriend acts all nutty. Mr. Tinkles obviously doesn’t realize that dogs make far greater pets than cats—who needs an animal that’s only nice to you when it wants to eat? We’ll have to deal with that once we have kid. Give us face-licking Fido any day of the week.