42. Vince Vaughn
Worst Performances: Psycho (1998), Domestic Disturbance (2001), Fred Claus (2007), Couples Retreat (2009), The Dilemma (2011)
We'll cut Vaughn some slack and overlook his embarrassing forays into dark seriousness (Gus Van Sant's pointless shot-for-shot Psycho remake, Domestic Disturbance). Instead, let's focus on his humor plate, post-2005, when, in Wedding Crashers, Vaughn made us genuinely laugh for the last time. Since then, he's slogged through insipid comedies like Fred Claus and Four Christmases, rehashing the same "smart-ass with feelings" persona he's been milking since 2003's Old School. Unless connected to Old School 2, announcements of new Vince Vaughn movies will continue to deflect from our ears.