#10. CHYLER LEIGH

TV show: Grey's Anatomy

A few years after her awkward debut in Not Another Teen Movie, Leigh went onto play the ABC medical drama's titular character's sexy little sister, Dr. Lexie Grey. Of course, it wouldn't be a medical series without inter-staff hook-ups in the break rooms and on empty hospital beds, which Leigh's done in abundance. It's easy to say we've learned a lot about this Grey's anatomy. Well, as much as basic cable allows us to, anyway.