22. Weeds (Showtime)
Mary-Louise Parker plays a sexy, widowed housewife who provides for her kids by pushing that sticky-icky in the 'burbs. A stellar supporting cast (including reliable comic foils Kevin Nealon, Elizabeth Perkins and Justin Kirk) made this one a must-watch.
YOU AUGHTA KNOW:
Weeds creator Jenji Kohan began her career by writing an episode of The Fresh Prince of Bel-Air in 1994.