5. Lost (ABC)
Survivors of a plane crash on a remote island try to find their way back to civilization while being plagued by a series of incomprehensibly bizarre circumstances, each more more WTF than the last. The biggest mindfuck on TV since Twin Peaks FUCKING EVER.
YOU AUGHTA KNOW:
Anything we say would be a spoiler, trust. Just get the DVDs and watch the damn show. And thank us later.