50 Cent vs. Floyd Mayweather, Jr.

Date: April 2008

What Happened: 50 Cent and Floyd Mayweather, Jr. were the best of friends at one point. But even best friends get into arguments. “Money” Mayweather, one of boxing’s best pound-for-pound fighters, got into a fight with 50 during a celebrity basketball event in Michigan.

In an interview with Hot 97’s Miss Jones, 50 says that he put his hands in Mayweather's face. As a natural reflex, Mayweather immediately threw a punch back. When asked about how the scuffle came about, he says they were arguing over a bet. Many wondered who won the fight between them. His response to Miss Jones’ question was confident as usual, “Floyd’s no longer undefeated.”