22. Sainte Marie
Address: 930 Poydras St.
Just a few months ago, Ste. Marie wouldn't have been included on this list. It's a restaurant with a giant bar that's a frequent stop on Sunday afternoons in the fall, due to its proximity to the Superdome, but it wasn't a drinking destination for most locals. However, the recent hire of Murf Reeves, one of NOLA's great cocktail men who helped establish Bar Tonique and Sylvain as exceptional drinking destinations (more on those two to come) vaults it onto the list. His presence has already paid dividends with a revamped cocktail menu that's full of goodness.