Hospital of the University of Pennsylvania
As Seen In: "Sweet Dee Has a Heart Attack" (Season 4); "A Very Sunny Christmas" (Season 6)
Location: 3400 Spruce St.
Dee is taken to this hospital after suffering a heart attack in Season 4, which transforms her and Dennis into the overzealous workout assholes you see too often at the gym. The hospital also appears in Season 6, when Frank is taken here after injuring his ankle in a car accident.
The Hospital of the University of Pennsylvania was founded at its Spruce Street location in 1874 by the University of Pennsylvania School of Medicine, which makes it the oldest university-owned teaching hospital in the country. On a more troubling note, singer David Ruffin died at the hospital in June of 1991 after reportedly passing out while smoking crack at a house in West Philly.