It’s no bueno to have absolutely zero control over yourself and your actions, so one major reason to refrain from smoking synthetic is that you might flip out and become a news story. It’s been well-documented that synthetic marijuana can trigger psychosis that lasts for months. One extreme case from over the summer found a 22-year-old man in Texas who began barking like a dog in a non-DMX fashion before chasing his family and neighbors. And then he went toe-to-toe with the family’s actual dog.
If it brings out the beast in you, just say no.