When it comes to comedy, Seth Rogen is as serious as cancer. Actually, the star of Knocked Up and Pineapple Express seems to think cancer is pretty fucking hilarious, which is why he’s producing and acting in Mandate Pictures’ I’m With Cancer, a comedy about a 25-year-old dude who finds out he has the disease.

The flick is based on producer and writer Will Reiser’s account of his struggle to beat cancer'and it’s sure to make laughter metastasize! Since it appears that absolutely nothing is off limits anymore, Complex thought up five more horribly offensive comedy ideas that are sure to get big laughs in Hollywood…

Distasteful theme: Genocide
Movie title: How They Hanging
Pitch:
A dictator from the inbred upper class (Danny DeVito) launches a campaign of ethnic cleansing only to realize that he’s exterminating the only people who can operate the complex machinery needed to produce the country’s chief export'bumper nuts. Can he sweet talk the few remaining survivors and convince them to keep the factories chock full o’ nuts?
Tagline: This mass murderer is killing ‘em…with kindness!

Distasteful theme: Rape/Abortion
Movie title: Who’s Your Daddy?
Pitch:
When a businesswoman (Tina Fey) is impregnated by a rapist, repealed abortion laws force her to keep the child. Can the precocious fetus (Billy Bob Thornton voiceover) that reminds her of being violated convince her that he’s a little bundle of joy before she puts fire to a hanger?
Tagline: Morning sickness isn’t the only thing making her vomit!

Distasteful theme: School Violence
Movie title: One Last Shot
Pitch:
Two sexually ambiguous high school outcasts (Frankie Muniz and Zac Efron) facing expulsion if they miss another day of class are desperate to make it to a midday Jonas Brothers mall appearance. Can they pull off a bloody cafeteria shooting, frame the chess team, and get classes canceled in time to catch the first harmonious note?
Tagline: School’s out…for memorial services!

Distasteful theme: Natural Disasters
Movie title: Let It Slide
Pitch:
When a Mexican family is left homeless by a landslide, the impossibly upbeat father (Al Pacino in face paint) vows to build them a mansion out of the same mud that ruined their lives!
Tagline: Who said dirt don’t hurt?

Distasteful theme: Hate Crimes
Movie title: Flame Thrown
Pitch:
A racist, homophobic minor league catcher (Marky Mark Wahlberg) with a swing developed by years of gay bashing is finally promised a big league gig'if only he can develop the club’s flamboyant new Cuban ace (Horatio Sanz)! Between pitching/catching jokes and pats on the ass, it’s gonna be hard to not assault his meal ticket!
Tagline: Can you catch “the gay”?